Heart failure subtypes: Pathophysiology and definitions

Pathophysiology of heart failure.

1 The pathophysiological definition of heart failure states that " cardiac failure is an inability of the heart to deliver blood (and therefore oxygen) at a rate commensurate with the requirements of the metabolising tissues at rest or during light exercise. This leads to characteristic systemic pathophysiological responses (neural, hormonal, renal and others), symptoms and signs.'' However, th...

Pathophysiology of Heart Failure

Cancer Therapy-Related Cardiac Dysfunction and Heart Failure: Part 1: Definitions, Pathophysiology, Risk Factors, and Imaging.

Advances in cancer therapy have resulted in significant improvement in long-term survival for many types of cancer but have also resulted in untoward side effects associated with treatment. One such complication that has become increasingly recognized is the development of cardiomyopathy and heart failure. Whether a previously healthy person from a cardiovascular perspective develops cancer the...

Pathophysiology of congestive heart failure.

Heart failure is a clinical syndrome characterized by impaired structure and/or function of the heart, leading to dyspnea and fatigue at rest or with exertion. The pathophysiology of heart failure is complex, and there is no single lesion. Any form of heart disease can lead to heart failure. Most heart failure can be explained by well-recognized etiologic factors, though ostensibly healthy pati...

Definitions, Epidemiology and Pathophysiology

Despite significant progress in the understanding and treatment of sepsis, it continues to be a major health problem in United States and around the world. Sepsis accounted for nearly 4,500 deaths (mortality rate 10%) and approximately $2 billion per year in healthcare expenditures in the U.S. alone. In this review, we will revisit the definitions of pediatric sepsis and discuss the epidemiolog...